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Polled R446



Background

Since 2009, the HornPolled-test has been available in Europe. This test was based on a HornPolled-test which was developed in the USA. In 2012, European geneticists have described the genetic test for HornPolled in much more detail. Scientific literature now describes two mutations that both cause the Polledness in cattle. Consequently, the genetic test for HornPolled is herewith almost completely finished. These two variants are indicated as follows:- Polledness Pc, this represents a mutation of Celtic origin.- Polledness Pf, this represents a mutation of Friesian origin.

Test specific information

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Age

The genetic factor is continuously present, and will always be visible.

Throughput

Normally the result can be expected within 25 working days. This turn-around-time starts when both the sample and the fully filled-out and signed submission form have been received.

Location of disease or trait

This genetic factor is linked to the presence of horns in cattle.

Breed dependence

For this test samples from all breeds are accepted.

Sample type

For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Blood Heparin, Tissue. Please contact PharmaDNA if you wish to submit other material as listed.

Result

An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will be horned. It cannot spread the polled mutation in the population. An animal can be carrier and has in that situation one horned and one polled allele. When used in breeding 50 percent of the offspring will receive the polled allele. Carriers are also polled. An animal can be affected and has in that situation two polled alleles. When used in breeding all offspring will also receive the polled allele. These animals are also polled.

Inheritance

This genetic factor is inherited in an autosomal, dominant, mode. This means, that the individual can be free of the mutation (homozygote normal), affected (homozygous affected) or carrier (heterozygous affected). Both carriers and affected individuals will show symptoms of the mutation.

Severity of Disease

Genetic characteristics are not a disease.